SEPT1 Antibody

Code CSB-PA270288
Size US$297
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  • Western blot analysis of extracts from Jurkat cells, using SEPT1 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SEPT1 Polyclonal antibody
Uniprot No.
Target Names
SEPT1
Alternative Names
DIFF6 antibody; Differentiation 6 (deoxyguanosine triphosphate triphosphohydrolase) antibody; LARP antibody; MGC20394 antibody; Peanut like protein 3 antibody; Peanut-like protein 3 antibody; PNUTL3 antibody; SEP1 antibody; SEPT1 antibody; SEPT1_HUMAN antibody; Septin 1 antibody; Septin-1 antibody; Serologically defined breast cancer antigen NY BR 24 antibody; Serologically defined breast cancer antigen NY-BR-24 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from internal of Human SEPT1.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential).
Gene References into Functions
  1. The SEPT1 may participate in cell-cell and/or cell-substrate interaction in DJM-1 and exert its function in a coordinated manner with other septins. PMID: 23087102
  2. Aurora-B binds and phosphorylates Septin1. PMID: 16179162
  3. An increase in Sept1 expression in all oral squamous-cell carcinoma-derived cell lines compared to human normal oral keratinocytes and oral premalignant lesions suggest that Sept1 expression could contribute to cancer progression, proliferation, or both. PMID: 17912427
Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Note=Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis.
Protein Families
TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
Tissue Specificity
Expressed at high levels in lymphoid and hematopoietic tissues.
Database Links

HGNC: 2879

OMIM: 612897

KEGG: hsa:1731

STRING: 9606.ENSP00000460441

UniGene: Hs.632176

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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