SEPT5 Antibody

Code CSB-PA030106
Size US$100
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Product Details

Uniprot No.
Target Names
SEPT5
Alternative Names
5 Sep antibody; CDCrel 1 antibody; CDCREL antibody; CDCrel-1 antibody; CDCREL1 antibody; Cell division control related protein 1 antibody; Cell division control-related protein 1 antibody; H5 antibody; HCDCREL 1 antibody; OTTHUMP00000197271 antibody; OTTHUMP00000197272 antibody; OTTHUMP00000197273 antibody; OTTHUMP00000197274 antibody; OTTHUMP00000197275 antibody; OTTHUMP00000197276 antibody; OTTHUMP00000197396 antibody; OTTHUMP00000197410 antibody; Peanut like 1 antibody; Peanut like 1 homolog antibody; Peanut like protein 1 antibody; Peanut-like protein 1 antibody; Platelet glycoprotein Ib beta chain antibody; PNUTL1 antibody; SEPT5 antibody; SEPT5_HUMAN antibody; Septin 5 antibody; Septin-5 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human Septin 5.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in platelet secretion.
Gene References into Functions
  1. CDCrel-1 overexpression exerts dopamine-dependent neurotoxicity and may contribute to the development of autosomal-recessive juvenile parkinsonism PMID: 14530399
  2. We studied the assembly of three human septins, SEPT4, SEPT5 and SEPT8, with each other (heterotypic) and with themselves (homotypic) using a yeast two-hybrid system. PMID: 15214843
  3. the high expression levels of PNUTL1 in human pancreatic endocrine cells that suggests a similar role of this protein in islet cells to that demonstrated in neuronal tissues, and warrants further functional studies of this protein. PMID: 16179808
  4. Our finding suggests a role for members of the septin family in the development of proliferative retinal membranes. PMID: 17625225
  5. HSP70 and constitutively active HSF1 mediate protection against CDCrel-1-mediated toxicity PMID: 18398426

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Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Note=In platelets, found in areas surrounding alpha-granules.
Protein Families
TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
Tissue Specificity
Expressed at high levels in the CNS, as well as in heart and platelets (at protein level).
Database Links

HGNC: 9164

OMIM: 602724

KEGG: hsa:5413

STRING: 9606.ENSP00000391311

UniGene: Hs.728762

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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