SF3A1 Antibody

Datasheet

Code	CSB-PA021121GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q15459

Target Names

SF3A1

Alternative Names

Pre mRNA processing 21 antibody; Pre mRNA splicing factor SF3a antibody; PRP21 antibody; PRPF21 antibody; SAP 114 antibody; SAP114 antibody; sf3a1 antibody; SF3A1_HUMAN antibody; SF3a120 antibody; Spliceosome associated protein 114 antibody; Spliceosome-associated protein 114 antibody; Splicing factor 3 subunit 1 antibody; Splicing factor 3a subunit 1 120kDa antibody; Splicing factor 3A subunit 1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human SF3A1

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB,IHC,IF

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes.

Gene References into Functions

Polymorphisms in SF3A1 gene is associated with pancreatic cancer. PMID: 26498691
SF3A1 polymorphisms are not associated with Colorectal Cancer Risk. PMID: 26079486
the SF3A mRNA splicing complex controls production of a negative regulator of TLR signaling that limits the extent of innate immune activation. PMID: 24204290
show that U1-SL4 interacts with the SF3A1 protein of the U2 snRNP PMID: 25403181
SF3a60, 66, and 120, but not SF1, are essential for pre-mRNA splicing PMID: 15647371

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Subcellular Location

Nucleus. Nucleus speckle.

Tissue Specificity

Ubiquitously expressed.

Database Links

HGNC: 10765

OMIM: 605595

KEGG: hsa:10291

STRING: 9606.ENSP00000215793

UniGene: Hs.406277

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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