SGSM1 Antibody

Code CSB-PA021201GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
SGSM1
Alternative Names
KIAA1941 antibody; RUN and TBC1 domain containing 2 antibody; RUN and TBC1 domain containing protein 2 antibody; RUN and TBC1 domain-containing protein 2 antibody; RUTBC2 antibody; Sgsm1 antibody; SGSM1_HUMAN antibody; Small G protein signaling modulator 1 antibody; Small G protein signaling modulator 1 protein antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human SGSM1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B.
Gene References into Functions
  1. These data show that RUTBC2 can act as a Rab36 GAP in cells and suggest that RUTBC2 links Rab9A function to Rab36 function in the endosomal system. PMID: 22637480
  2. Identification of novel protein SGSM1 which modulate small G protein (RAP and RAB)-mediated signaling pathway. PMID: 17509819
Subcellular Location
Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm.
Protein Families
RUTBC family
Tissue Specificity
Mainly expressed in brain, heart and testis.
Database Links

HGNC: 29410

OMIM: 611417

KEGG: hsa:129049

STRING: 9606.ENSP00000383212

UniGene: Hs.474397

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