SLC22A9 Antibody

1. two human organic anion transporters OAT2 and OAT7 activities were assessed. PMID: 28945155
2. Pravastatin is the first identified OAT7 drug substrate. Substantial inter-individual variability in hepatic OAT7 expression, majorly driven by HNF4alpha, may contribute to pravastatin drug disposition and might affect response. PMID: 26239079
3. uptake of steroid sulfates by isolated trophoblasts is mediated by OATP-B and OAT-4 suggesting a physiological role of both carrier proteins in placental uptake of fetal-derived steroid sulfates. PMID: 12409283
4. Both progesterone and activation of PKC inhibited hOAT4 activity through redistribution of the transporter from cell surface to the intracellular compartments. PMID: 17341544
5. OAT7 is the first liver-specific transporter among members of the organic anion transporters of SLC22 family. PMID: 17393504
6. The data provide a model for the concerted action of OAT1 mediating apical secretion of glutarate derivatives from proximal tubule cells PMID: 18365245
7. The regulatory single nucleotide polymorphism (SNP) of OAT4 found in the promoter region of nephrectomized patients is unlikely to influence mRNA expression or promoter activity of OAT4. PMID: 18414781
8. Review summarizes current knowledge on the functional and phenotypic consequences of genetic variation in intestinally, hepatically and renally expressed members of solute carrier family (SLC22) member 9. PMID: 18466105
9. Functional differences in steroid uptake of SLC22A9 and SLC02B1 in human placenta are reported. PMID: 18501590
10. Human organic anion transporter hOAT4 is a transporter of perfluorooctanoic acid. PMID: 19371258

Show More

Hide All

HGNC: 16261

OMIM: 607579

KEGG: hsa:114571

STRING: 9606.ENSP00000279178

UniGene: Hs.502772