SLC9A9 Antibody

1. downregulation of miR-135a as a potential mechanism underlying the high NHE9 expression observed in subset of glioblastomas PMID: 29268774
2. SLC9A9 is a sodium hydrogen exchanger present in the recycling endosome and highly expressed in the brain. PMID: 27439572
3. SLC9A9 has an oncogenic function by being related to EGFR signaling, suggesting SLC9A9 may be a novel prognostic indicator and a therapeutic target in colorectal cancer PMID: 28476790
4. Ectopic expression of NHE9 in human brain microvascular endothelial cells without external cues induced up-regulation of the transferrin receptor (TfR) and down-regulation of ferritin, leading to an increase in iron uptake PMID: 28130443
5. Taken together, our findings demonstrate that NHE9 can be an effective predictor of chemoradiotherapy response in esophageal squamous cell carcinoma PMID: 25915159
6. the expression of SLC9A9 can be a prognostic predictor for ESCC. PMID: 25835977
7. SLC9A9 appears to influence the differentiation of T cells to a proinflammatory fate and may have a broader role in multiple sclerosis disease activity. There is an association between rs9828519(G) and nonresponse to IFNbeta treatment. PMID: 25914168
8. find interesting gene expression changes in endosomal NHE6 and NHE9 in postmortem autism brains. PMID: 23508127
9. Loss-of-function mutations in NHE9 may contribute to autistic phenotype by modulating synaptic membrane protein expression and neurotransmitter clearance. PMID: 24065030
10. 33 directly measured and 13 derived glycosylation traits in 3533 individuals were identified and three novel gene association (MGAT5, B3GAT1 and SLC9A9) were identified using an additional European cohort. PMID: 21908519
11. SLC9A9 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells. PMID: 21555518
12. This review defines NHE6-9 as organellar NHEs that are fairly dynamic, implying that they are subjected to intracellular trafficking and thus they continuously shuttle between organelles and the plasma membrane. PMID: 21171650
13. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20732626
14. results suggest that SLC9A9 may be related to hyperactive-impulsive symptoms in AD/HD and the disruption of SLC9A9 may be responsible for the behavioral phenotype observed in the inversion family PMID: 20032819
15. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
16. Observational study of gene-disease association. (HuGE Navigator) PMID: 20032819
17. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19268276
18. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 18937294
19. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 18821565
20. Observational study of gene-disease association. (HuGE Navigator) PMID: 18649358

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HGNC: 20653

OMIM: 608396

KEGG: hsa:285195

STRING: 9606.ENSP00000320246

UniGene: Hs.302257