SPIC Antibody

Code CSB-PA818708LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA818708LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA818708LA01HU at dilution of 1:100

  • Western Blot
    Positive WB detected in: Mouse heart tissue, Mouse liver tissue
    All lanes: SPIC antibody at 3.4µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 30 kDa
    Observed band size: 30 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) SPIC Polyclonal antibody
Uniprot No.
Target Names
SPIC
Alternative Names
AU019198 antibody; C76795 antibody; MGC40611 antibody; MGC80555 antibody; Prf antibody; Pu.1 related factor antibody; Spi C antibody; Spi C transcription factor antibody; Spi-C transcription factor (Spi-1/PU.1 related) antibody; spiC antibody; SPIC_HUMAN antibody; Transcription factor Spi-C antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Transcription factor Spi-C protein (1-248AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The SPIC Antibody (Product code: CSB-PA818708LA01HU) is Non-conjugated. For SPIC Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA818708LB01HU SPIC Antibody, HRP conjugated ELISA
FITC CSB-PA818708LC01HU SPIC Antibody, FITC conjugated
Biotin CSB-PA818708LD01HU SPIC Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.
Gene References into Functions
  1. A protein interaction between SPI-C and STAT6 is the basis for a novel mechanism for regulation of IL4 induced gene expression. PMID: 16647686
Subcellular Location
Nucleus.
Protein Families
ETS family
Tissue Specificity
Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.
Database Links

HGNC: 29549

OMIM: 612568

KEGG: hsa:121599

STRING: 9606.ENSP00000299272

UniGene: Hs.577097

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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