SPIC Antibody

Code CSB-PA004137
Size US$100
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  • Western Blot analysis of HeLa cells using Spi-C Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
SPIC
Alternative Names
AU019198 antibody; C76795 antibody; MGC40611 antibody; MGC80555 antibody; Prf antibody; Pu.1 related factor antibody; Spi C antibody; Spi C transcription factor antibody; Spi-C transcription factor (Spi-1/PU.1 related) antibody; spiC antibody; SPIC_HUMAN antibody; Transcription factor Spi-C antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human Spi-C.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.
Gene References into Functions
  1. A protein interaction between SPI-C and STAT6 is the basis for a novel mechanism for regulation of IL4 induced gene expression. PMID: 16647686
Subcellular Location
Nucleus.
Protein Families
ETS family
Tissue Specificity
Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.
Database Links

HGNC: 29549

OMIM: 612568

KEGG: hsa:121599

STRING: 9606.ENSP00000299272

UniGene: Hs.577097

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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