SPRR1A Antibody

Datasheet

Code	CSB-PA022610LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human cervical cancer using CSB-PA022610LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA022610LA01HU at dilution of 1:100 Immunofluorescent analysis of HepG2 cells using CSB-PA022610LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SPRR1A Polyclonal antibody

Uniprot No.

P35321

Target Names

SPRR1A

Alternative Names

SPRR1A antibody; Cornifin-A antibody; 19 kDa pancornulin antibody; SPRK antibody; Small proline-rich protein IA antibody; SPR-IA antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Cornifin-A protein (8-72AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The SPRR1A Antibody (Product code: CSB-PA022610LA01HU) is Non-conjugated. For SPRR1A Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA022610LB01HU	SPRR1A Antibody, HRP conjugated	ELISA
FITC	CSB-PA022610LC01HU	SPRR1A Antibody, FITC conjugated
Biotin	CSB-PA022610LD01HU	SPRR1A Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.

Gene References into Functions

mRNA levels of LELP1, SPRR1Av1, and SPRR1Av2 were significantly higher in the skin of patients with AD compared with the control group. PMID: 27304082
the SPRR1A status might play an important role in the prognosis of postmenopausal breast carcinoma patients, especially that of progesterone receptor-positive subgroups. PMID: 25424702
A expression may be useful as a prognostic factor for diffuse large B-cell lymphoma. PMID: 24886019
Association of psoriasis to PGLYRP and SPRR genes at PSORS4 locus on 1q shows heterogeneity between Finnish, Swedish and Irish families. PMID: 18643845
the deregulated increase in SPRR1A expression in chronic atopic skin lesions reflects an insufficient rise in SPRR transcripts, unable to compensate for the lack of LOR and thus contributing to the persistence of chronic atopic dermatitis skin lesions. PMID: 19672094

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Subcellular Location

Cytoplasm.

Protein Families

Cornifin (SPRR) family

Database Links

HGNC: 11259

OMIM: 182265

KEGG: hsa:6698

STRING: 9606.ENSP00000307340

UniGene: Hs.46320

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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