SRPK3 Antibody

Code CSB-PA008774
Size US$100
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Product Details

Uniprot No.
Target Names
SRPK3
Alternative Names
MSSK-1 antibody; MSSK1 antibody; Muscle specific serine kinase 1 antibody; Muscle-specific serine kinase 1 antibody; Serine/arginine rich protein specific kinase 3 antibody; Serine/arginine-rich protein-specific kinase 3 antibody; Serine/threonine protein kinase 23 antibody; Serine/threonine protein kinase SRPK3 antibody; Serine/threonine-protein kinase 23 antibody; SFRS protein kinase 3 antibody; SR-protein-specific kinase 3 antibody; Srpk3 antibody; SRPK3_HUMAN antibody; SRSF protein kinase 3 antibody; STK 23 antibody; STK23 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human SRPK3.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development.
Gene References into Functions
  1. SRPK3 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
  2. Alternative splicing of the alpha-exon of MEF2C regulates myogenesis. Loss of SRPK3 in rhabdomyosarcoma cells inhibits this splicing and blocks differentiation. PMID: 25404735
Protein Families
Protein kinase superfamily, CMGC Ser/Thr protein kinase family
Tissue Specificity
Exclusively expressed in skeletal and heart muscle.
Database Links

HGNC: 11402

OMIM: 301002

KEGG: hsa:26576

STRING: 9606.ENSP00000359119

UniGene: Hs.104865

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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