SRPK3 Antibody

Code CSB-PA008774
Size US$119
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Product Details

Uniprot No.
Target Names
SRPK3
Alternative Names
MSSK-1 antibody; MSSK1 antibody; Muscle specific serine kinase 1 antibody; Muscle-specific serine kinase 1 antibody; Serine/arginine rich protein specific kinase 3 antibody; Serine/arginine-rich protein-specific kinase 3 antibody; Serine/threonine protein kinase 23 antibody; Serine/threonine protein kinase SRPK3 antibody; Serine/threonine-protein kinase 23 antibody; SFRS protein kinase 3 antibody; SR-protein-specific kinase 3 antibody; Srpk3 antibody; SRPK3_HUMAN antibody; SRSF protein kinase 3 antibody; STK 23 antibody; STK23 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human SRPK3.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains. Phosphorylates the SR splicing factor SRSF1 and the lamin-B receptor (LBR) in vitro. Required for normal muscle development.
Gene References into Functions
  1. SRPK3 expression is significantly downregulated in human masticatory mucosa during wound healing PMID: 28005267
  2. Alternative splicing of the alpha-exon of MEF2C regulates myogenesis. Loss of SRPK3 in rhabdomyosarcoma cells inhibits this splicing and blocks differentiation. PMID: 25404735
Protein Families
Protein kinase superfamily, CMGC Ser/Thr protein kinase family
Tissue Specificity
Exclusively expressed in skeletal and heart muscle.
Database Links

HGNC: 11402

OMIM: 301002

KEGG: hsa:26576

STRING: 9606.ENSP00000359119

UniGene: Hs.104865

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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