STAU2 Antibody

Datasheet

Code	CSB-PA022819GA01HU
Size	$600
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Product Details
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Target Background

Product Details

Uniprot No.

Q9NUL3

Target Names

STAU2

Alternative Names

39K2 antibody; 39K3 antibody; DKFZp781K0371 antibody; Double stranded RNA binding protein Staufen homolog 2 antibody; Double-stranded RNA-binding protein Staufen homolog 2 antibody; MGC119606 antibody; STAU 2 antibody; stau2 antibody; STAU2_HUMAN antibody; Staufen (Drosophila; RNA-binding protein) homolog 2 antibody; Staufen double-stranded RNA binding protein 2 antibody; Staufen homolog 2 antibody; Staufen RNA binding protein homolog 2 antibody; Staufen; RNA binding protein; homolog 2 (Drosophila) antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human STAU2

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

RNA-binding protein required for the microtubule-dependent transport of neuronal RNA from the cell body to the dendrite. As protein synthesis occurs within the dendrite, the localization of specific mRNAs to dendrites may be a prerequisite for neurite outgrowth and plasticity at sites distant from the cell body.

Gene References into Functions

during genotoxic stress, Stau2 is downregulated at the promoter level in an ATR- and E2F1-dependent manner, leading to increased levels of DNA damage and apoptosis. PMID: 26843428
Authors establish that human Staufen-2, a host factor which is up-regulated upon HIV-1 infection, interacts with HIV-1 Rev, thereby promoting its RNA export activity and progeny virus formation. PMID: 24520823
Staufen2 functions in Staufen1-mediated mRNA decay by binding to itself and its paralog and promoting UPF1 helicase but not ATPase activity. PMID: 23263869
We suggest a role for Stau2 in the generation and regulation of Map1b mRNA containing granules that are required for mGluR-long-term depression PMID: 21508097
Data show that Stau2 is localized to the neuronal soma and dendrites, but it does not colocalize with Stau1-containing particles. PMID: 12140260
Stau1- and Stau2-mRNPs associate with distinct but overlapping sets of cellular mRNAs. PMID: 18094122

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Subcellular Location

Cytoplasm. Nucleus. Nucleus, nucleolus. Endoplasmic reticulum.

Database Links

HGNC: 11371

OMIM: 605920

KEGG: hsa:27067

STRING: 9606.ENSP00000428756

UniGene: Hs.561815

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Phage Display Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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