STMN2 Antibody

1. RARB and STMN2 polymorphisms were not associated with sporadic CJD in the Korean population. PMID: 24414001
2. STMN and SCG10 are similarly targeted by JNK but there are clear differences in JNK recognition and phosphorylation of the closely related family member, SCLIP. PMID: 24589734
3. SCG10 is upregulated in the IKAP/Elp1-deficient familial dysautonomia cerebrum lending support to the concept that SCG10 elevation can alter the microtubule organization and dynamics PMID: 21273291
4. Overexpression of SCG10 is associated with Liver Fibrosis. PMID: 20802173
5. RGS6 interacts with this protein and promotes neuronal differentiation; role of the G gamma subunit-like (GGL) domain of RGS6 PMID: 12140291
6. STMN2 is required for maintaining the anchorage-independent growth state of beta-catenin/TCF-activated hepatoma cells PMID: 16712787
7. activity at opposite microtubule ends may play role role in regulating growth cone microtubules; ability to promote plus end growth may facilitate microtubule extension; ability to destabilize minus ends may provide tubulin for net plus end elongation PMID: 17311410
8. Review proposes a model reconciling the microtubule regulatory properties of superior cervical ganglion protein 10 with its role as a c-Jun N-terminal kinase 1 (JNK1) effector of regeneration. PMID: 18076368
9. BRI3 associates with SCG10 and attenuates NGF-induced neurite outgrowth in PC12 cells. PMID: 18452648
10. SCLIP and SCG10 were colocalized to the Golgi apparatus of chromaffin cells in vivo and shared localization with CHGA as it transited the Golgi. PMID: 18549247
11. STMN2 appears a novel marker of osteogenesis and osteoblast per se, that could play a role in the regulation of the adipocyte/osteoblast balance. PMID: 18611392
12. SCG10 acts as an effector downstream of Rnd1 to regulate axon extensions by modulating microtubule organization. PMID: 18996843

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HGNC: 10577

OMIM: 600621

KEGG: hsa:11075

STRING: 9606.ENSP00000429243

UniGene: Hs.521651