TAF5 Antibody

Code CSB-PA613596ESR1HU
Size US$166
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Image
  • Western blot
    All lanes: TAF5 antibody at 2.33µg/ml
    Lane 1: Hela whole cell lysate
    Lane 2: HepG2 whole cell lysate
    Lane 3: MCF-7 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 87, 81 kDa
    Observed band size: 87 kDa

  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA613596ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TAF5 Polyclonal antibody
Uniprot No.
Target Names
TAF5
Alternative Names
TAF5 antibody; TAF2D antibody; Transcription initiation factor TFIID subunit 5 antibody; Transcription initiation factor TFIID 100 kDa subunit antibody; TAF(II)100 antibody; TAFII-100 antibody; TAFII100 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Transcription initiation factor TFIID subunit 5 protein (656-800AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription. TAF5/TAFII100 interacts strongly with the histone H4-related TAF6/TAFII80 and the histone H3-related TAF9/TAFII31, as well as a stable complex comprised of both TAF5/TAFII80 and TAF6/TAFII31. Apparently weaker interactions of TAF5/TAFII100 with TBP, TAF1/TAFII250, TAF11/TAFII28, and TAF12/TAFII20, but not TAF7/TAFII55, also have been observed.
Gene References into Functions
  1. TFIID TAF6-TAF9 complex formation involves the HEAT repeat-containing C-terminal domain of TAF6 and is modulated by TAF5 protein. PMID: 22696218
  2. reversible SUMO modification at hsTAF5 contributes to the dynamic regulation of TFIID promoter-binding activity in human cells PMID: 15637059
  3. TAF5 protein demonstrates the ability of the N-terminal half of the TAF5 gene to form a flexible, extended dimer, a key property required for the assembly of the TFIID complex PMID: 17227857
Subcellular Location
Nucleus.
Protein Families
WD repeat TAF5 family
Database Links

HGNC: 11539

OMIM: 601787

KEGG: hsa:6877

STRING: 9606.ENSP00000358854

UniGene: Hs.96103

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