TAX1BP3 Antibody

1. Mutations in TAX1BP3 cause dilated cardiomyopathy with septo-optic dysplasia PMID: 25645515
2. ARHGEF7, a guanine nucleotide exchange factor for Rho GTPases, as one novel TIP-1-interacting protein in human glioblastoma cells PMID: 23563176
3. this study reports the identification of two new hGIP-interacting partners, DTX1 and STAU1. PMID: 23395680
4. The study provided the first evidence showing that TIP-1 modulates p53 protein stability and is involved in the radioresistance of malignant gliomas. PMID: 23028987
5. The study reports the identification of 18 new glutaminase-interacting protein - binding peptides with novel internal motifs that map to a number of candidate human glutaminase-interacting protein partner proteins. PMID: 22876914
6. this study revealed a novel oncogenic function of TIP-1 suggesting that TIP-1 holds potential as a prognostic biomarker and a therapeutic target in the treatment of human invasive breast cancers. PMID: 22564736
7. HPV16 E6, Tip-1 and ARHGEF16 may cooperate to activate Cdc42 and support a potential link between the expression of HPV16 E6 and Cdc42 activation. PMID: 21139582
8. This is the first study reporting BAI2 as an interaction partner of GIP. PMID: 21787750
9. TIP-1 may represent a novel regulatory element in the Wnt/beta-catenin signaling pathway PMID: 12874278
10. HPV16 E6 protein may increase cell motility by augmenting GTP RhoA mediated activation of RhoA kinases and that this is dependent on the expression of the Tip-1 protein PMID: 15492812
11. TIP-1 is ubiquitously expressed, raising the possibility that TIP-1 may play a similar role in regulating the expression of other membrane proteins containing a type I PDZ ligand. PMID: 16855024
12. the overexpression, efficient refolding, single-step purification, and biophysical characterization of recombinant human TIP-1 with three different C-terminal target protein recognition sequence motifs by CD, fluorescence, and NMR methods PMID: 18690705
13. TIP-1 may act as an important regulator for the endocytic pathway of Kir2.3. PMID: 19635485

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HGNC: 30684

OMIM: 616476

KEGG: hsa:30851

STRING: 9606.ENSP00000225525

UniGene: Hs.12956