TAX1BP3, also known as Tax1 binding protein 3, is a significant protein with multiple aliases including CCZF, Cezanne-2, and ZFCC1. It plays a crucial role in regulating the immune response and cell survival. TAX1BP3 acts as a negative regulator of NF-κB signaling pathway by interacting with TRAF6, thus modulating inflammation and apoptosis.
Defects in TAX1BP3 are associated with various diseases such as autoimmune disorders. In drug development, researchers are exploring its potential as a therapeutic target. By understanding its precise mechanism, novel drugs may be developed to treat related diseases and improve patient outcomes.
Recombinant Human Tax1-binding protein 3 (TAX1BP3) (CSB-RP044454h)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TAX1BP3 Antibody (CSB-PA04445A0Rb)
Validated Data
Western blot
All lanes: TAX1BP3 antibody at 2µg/ml
Lane 1: EC109 whole cell lysate
Lane 2: 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/15000 dilution
Predicted band size: 14 kDa
Observed band size: 70 kDa
The following TAX1BP3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
TAX1BP3 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA04445A0Rb | TAX1BP3 Antibody | Human | ELISA, WB |
CSB-PA023180GA01HU | TAX1BP3 Antibody | Human,Mouse,Rat | ELISA,WB |
TAX1BP3 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP023180HU CSB-EP023180HU CSB-BP023180HU CSB-MP023180HU CSB-EP023180HU-B |
Recombinant Human Tax1-binding protein 3 (TAX1BP3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-RP044454h | Recombinant Human Tax1-binding protein 3 (TAX1BP3) | E.coli |