TBL1Y Antibody

Datasheet

Code	CSB-PA047135
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA047135(TBL1Y Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA047135(TBL1Y Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9BQ87

Target Names

TBL1Y

Alternative Names

F-box-like/WD repeat-containing protein TBL1Y antibody; TBL1 antibody; TBL1Y antibody; TBL1Y_HUMAN antibody; Transducin (beta) like 1; Y linked antibody; Transducin beta-like 1 antibody; Transducin beta-like protein 1Y antibody; Transducin-beta-like protein 1 antibody; Transducin-beta-like protein 1; Y-linked antibody; Y-linked antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Fusion protein of Human TBL1Y

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
IHC	1:25-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange.

Gene References into Functions

reducing TBL1Y cellular level using siRNA approach influenced cardiac differentiation by reducing its efficacy as well as increasing the probability of impaired contractions; proposed reclassification of TBL1Y as "found missing protein" PMID: 28853286
Our findings suggest that TBL1Y is involved in the genesis of non-syndromic coarctation of the aorta. PMID: 22280357
Taken together,these findings suggest that TBL1 controls NF-kB activation by recruiting NF-kB to its target gene promoter. PMID: 21189284
investigated 12 single-nucleotide polymorphisms in Y-linked neuroligin 4, transducin b-like 1, and eukaryotic translation initiation factor 1a genes, results suggest a Y chromosome effect in autism PMID: 19605777

Subcellular Location

Nucleus.

Protein Families

WD repeat EBI family

Tissue Specificity

Fetal brain and prostate. Expressed in the cochlear spiral ganglion neurons, and in outer and inner hair cells.

Database Links

HGNC: 18502

OMIM: 400033

KEGG: hsa:90665

STRING: 9606.ENSP00000328879

UniGene: Hs.664560

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Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Wnt signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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