TENM3 Antibody

Datasheet

Code	CSB-PA012753
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA012753(TENM3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA012753(TENM3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9P273

Target Names

TENM3

Alternative Names

FLJ10474 antibody; FLJ10886 antibody; KIAA1455 antibody; odd Oz Ten m homolog 3 antibody; odz odd Oz ten m homolog 3 (Drosophila) antibody; odz odd Oz ten m homolog 3 antibody; ODZ3 like protein antibody; Protein Odd Oz ten m homolog 3 antibody; Protein Odd Oz/ten-m homolog 3 antibody; Ten 3 antibody; Ten M3 antibody; Ten-3 antibody; Ten-m3 antibody; TEN3_HUMAN antibody; Tenascin M3 antibody; Tenascin-M3 antibody; Teneurin 3 antibody; Teneurin transmembrane protein 3 antibody; Teneurin-3 antibody; Teneurin3 antibody; tenm3 antibody; TNM3 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthetic peptide of Human TENM3

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:3000-1:10000
IHC	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Involved in neural development by regulating the establishment of proper connectivity within the nervous system. Acts in both pre- and postsynaptic neurons in the hippocampus to control the assembly of a precise topographic projection: required in both CA1 and subicular neurons for the precise targeting of proximal CA1 axons to distal subiculum, probably by promoting homophilic cell adhesion. Required for proper dendrite morphogenesis and axon targeting in the vertebrate visual system, thereby playing a key role in the development of the visual pathway. Regulates the formation in ipsilateral retinal mapping to both the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC). May also be involved in the differentiation of the fibroblast-like cells in the superficial layer of mandibular condylar cartilage into chondrocytes.

Gene References into Functions

This report supports the association of TENM3 mutations with colobomatous microphthalmia and expands the phenotypic spectrum associated with mutations in this gene PMID: 27103084
Null mutation in ODZ3 causes autosomal recessive microphthalmia in humans. PMID: 22766609

Involvement in disease

Microphthalmia, isolated, with coloboma, 9 (MCOPCB9)

Subcellular Location

Cell membrane; Single-pass membrane protein. Cell projection, axon.

Protein Families

Tenascin family, Teneurin subfamily

Tissue Specificity

Expressed in adult and fetal brain, slightly lower levels in testis and ovary, and intermediate levels in all other peripheral tissues examined. Not expressed in spleen or liver. Expression was high in brain, with highest levels in amygdala and caudate nu

Database Links

HGNC: 29944

OMIM: 610083

KEGG: hsa:55714

STRING: 9606.ENSP00000385276

UniGene: Hs.130438

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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