THOC7 Antibody

Code CSB-PA876114
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA876114(THOC7 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Mouse spleen tissue, human fetal liver tissue, hela cells, mouse testis tissue, A431 cells, Primary antibody: CSB-PA876114(THOC7 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 15 seconds
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Product Details

Uniprot No.
Target Names
THOC7
Alternative Names
FLJ23445 antibody; fSAP24 antibody; Functional spliceosome associated protein 24 antibody; Functional spliceosome-associated protein 24 antibody; hTREX30 antibody; Ngg1 interacting factor 3 like 1 binding protein 1 antibody; Ngg1 interacting factor 3 like protein 1 binding protein 1 antibody; Ngg1-interacting factor 3-like protein 1-binding protein 1 antibody; NIF3L1 binding protein 1 antibody; NIF3L1-binding protein 1 antibody; NIF3L1BP1 antibody; THO complex 7 homolog (Drosophila) antibody; THO complex 7 homolog antibody; THO complex subunit 7 homolog antibody; THOC 7 antibody; thoc7 antibody; THOC7_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human THOC7
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
WB 1:500-1:2000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.; The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
Gene References into Functions
  1. THOC7 (50-137, amino acid numbers) binds to the N-terminal portion (1-199) of FMIP directly. PMID: 19059247
Subcellular Location
Cytoplasm. Nucleus. Nucleus speckle.
Protein Families
THOC7 family
Database Links

HGNC: 29874

OMIM: 611965

KEGG: hsa:80145

STRING: 9606.ENSP00000295899

UniGene: Hs.288151

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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