TIMM44 Antibody

Code CSB-PA023555GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
TIMM44
Alternative Names
TIMM44 antibody; MIMT44 antibody; TIM44 antibody; Mitochondrial import inner membrane translocase subunit TIM44 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human TIMM44
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Recruits mitochondrial HSP70 to drive protein translocation into the matrix using ATP as an energy source.
Gene References into Functions
  1. TIM44 was identified for the first time as a potential oncogene, which plays an important role in autophagy through the TIM44-SOD2-ROS-mTOR pathway. PMID: 27849558
  2. The Timm44 gene may be a new target for the treatment of type 2 diabetes PMID: 25749183
  3. This protein has been found differentially expressed in thalami from patients with schizophrenia. PMID: 20471030
Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side. Mitochondrion matrix.
Protein Families
Tim44 family
Database Links

HGNC: 17316

OMIM: 605058

KEGG: hsa:10469

STRING: 9606.ENSP00000270538

UniGene: Hs.465784

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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