TMF1 Antibody

Code CSB-PA023904GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
TMF1
Alternative Names
Androgen receptor coactivator 160 kDa protein antibody; Androgen receptor-associated protein of 160 kDa antibody; ARA160 antibody; TATA element modulatory factor 1 antibody; TATA element modulatory factor antibody; TMF antibody; Tmf1 antibody; TMF1_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human TMF1-Specific
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Potential coactivator of the androgen receptor. Mediates STAT3 degradation. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. This protein binds the HIV-1 TATA element and inhibits transcriptional activation by the TATA-binding protein (TBP).
Gene References into Functions
  1. In patient with chronic granulomatous disease, a 5.8-kb, incomplete and partly exonized TMF1 transcript was identified in intron 1 of CYBB, in opposite orientation to the host gene. PMID: 24478191
  2. COG complex interacts with two different Rabs in addition to each end of the golgin "TATA element modulatory factor" (TMF). PMID: 23239882
  3. These observations suggest critical roles for TMF in two Rab6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the endoplasmic reticulum. PMID: 17698061
  4. Overexpression of TMF/ARA160 downregulates proangiogenic genes and attenuates the progression of prostate cancer xenografts. PMID: 19330832
Subcellular Location
Cytoplasm. Nucleus. Golgi apparatus membrane. Note=Concentrated at the budding structures localized at the tips of cisternae.
Database Links

HGNC: 11870

OMIM: 601126

KEGG: hsa:7110

STRING: 9606.ENSP00000381567

UniGene: Hs.267632

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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