TRAK2 Antibody

Datasheet

Code	CSB-PA050107
Size	US$119
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

O60296

Target Names

TRAK2

Alternative Names

ALS2CR 3 antibody; ALS2CR3 antibody; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 3 antibody; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein antibody; CALS C antibody; GRIF 1 antibody; GRIF1 antibody; KIAA0549 antibody; OIP98 antibody; Trafficking kinesin-binding protein 2 antibody; Trafficking protein kinesin binding 2 antibody; Trak2 antibody; TRAK2_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of Human GRIF-1.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

IHC, ELISA

Recommended Dilution

Application	Recommended Dilution
IHC	1:100-1:300
ELISA	1:10000

Protocols

Immunohistochemistry (IHC) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.

Gene References into Functions

This study showed that the TRAK2 was more prevalent in dendrites of hippocampal neurons. In cortical neurons, TRAK2 was equally distributed between axons and dendrites. PMID: 25653102
The results of this study established a key role for mammalian TRAK2 proteins in axonal and dendritic targeting of mitochondria. PMID: 23395375
identification, molecular cloning and characterization PMID: 12034717
GRIF-1 and OIP106 have roles in protein and/or organelle transport in excitable cells in a manner analogous to glutamate receptor-interacting-protein 1 PMID: 15644324
analysis of the GRIF-1 binding domain of the kinesin, KIF5C, which substantiates a role for GRIF-1 as an adaptor protein in the anterograde trafficking of cargoes PMID: 16835241
Binds to Kir2.1 and facilitates trafficking of this channel to the cell surface. PMID: 16895905

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Subcellular Location

Cytoplasm. Early endosome. Mitochondrion.

Tissue Specificity

Widely expressed, with highest expression in heart.

Database Links

HGNC: 13206

OMIM: 607334

KEGG: hsa:66008

STRING: 9606.ENSP00000328875

UniGene: Hs.152774

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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