TRAK2 Antibody

Code CSB-PA024220GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
TRAK2
Alternative Names
ALS2CR 3 antibody; ALS2CR3 antibody; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 3 antibody; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 3 protein antibody; CALS C antibody; GRIF 1 antibody; GRIF1 antibody; KIAA0549 antibody; OIP98 antibody; Trafficking kinesin-binding protein 2 antibody; Trafficking protein kinesin binding 2 antibody; Trak2 antibody; TRAK2_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human TRAK2
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May regulate endosome-to-lysosome trafficking of membrane cargo, including EGFR.
Gene References into Functions
  1. This study showed that the TRAK2 was more prevalent in dendrites of hippocampal neurons. In cortical neurons, TRAK2 was equally distributed between axons and dendrites. PMID: 25653102
  2. The results of this study established a key role for mammalian TRAK2 proteins in axonal and dendritic targeting of mitochondria. PMID: 23395375
  3. identification, molecular cloning and characterization PMID: 12034717
  4. GRIF-1 and OIP106 have roles in protein and/or organelle transport in excitable cells in a manner analogous to glutamate receptor-interacting-protein 1 PMID: 15644324
  5. analysis of the GRIF-1 binding domain of the kinesin, KIF5C, which substantiates a role for GRIF-1 as an adaptor protein in the anterograde trafficking of cargoes PMID: 16835241
  6. Binds to Kir2.1 and facilitates trafficking of this channel to the cell surface. PMID: 16895905

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Subcellular Location
Cytoplasm. Early endosome. Mitochondrion.
Tissue Specificity
Widely expressed, with highest expression in heart.
Database Links

HGNC: 13206

OMIM: 607334

KEGG: hsa:66008

STRING: 9606.ENSP00000328875

UniGene: Hs.152774

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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