TRIM10 Antibody

Code CSB-PA242603
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA242603(TRIM10 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA242603(TRIM10 Antibody) at dilution 1/35, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA242603(TRIM10 Antibody) at dilution 1/800 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 30 seconds
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Product Details

Uniprot No.
Target Names
TRIM10
Alternative Names
TRIM10 antibody; RFB30 antibody; RNF9 antibody; Tripartite motif-containing protein 10 antibody; B30-RING finger protein antibody; RING finger protein 9 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Fusion protein of Human TRIM10
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:10000
WB 1:1000-1:5000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
E3 ligase that plays an essential role in the differentiation and survival of terminal erythroid cells. May directly bind to PTEN and promote its ubiquitination, resulting in its proteasomal degradation and activation of hypertrophic signaling. In addition, plays a role in immune response regulation by repressing the phosphorylation of STAT1 and STAT2 in the interferon/JAK/STAT signaling pathway independent of its E3 ligase activity. Mechanistically, interacts with the intracellular domain of IFNAR1 and thereby inhibits the association between TYK2 and IFNAR1.
Subcellular Location
Cytoplasm.
Protein Families
TRIM/RBCC family
Database Links

HGNC: 10072

OMIM: 605701

KEGG: hsa:10107

STRING: 9606.ENSP00000397073

UniGene: Hs.709483

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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