TSHZ1 Antibody

Code CSB-PA025135GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
TSHZ1
Alternative Names
TSHZ1 antibody; SDCCAG33 antibody; TSH1 antibody; Teashirt homolog 1 antibody; Antigen NY-CO-33 antibody; Serologically defined colon cancer antigen 33 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human TSHZ1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential).
Gene References into Functions
  1. TSHZ1 levels are reduced in human islets of donors with type 2 diabetes PMID: 25918232
  2. TSHZ1 is a key regulator of mammalian olfactory bulb development and function and controls the expression of PROKR2. PMID: 24487590
  3. Together, these results demonstrate that hemizygosity of TSHZ1 leads to congenital aural atresia as a result of haploinsufficiency PMID: 22152683
  4. a significant up-regulation of BORIS (p<0.001) and TSHZ1 transcripts (p<0.05) for JAs compared to nasal mucosa. PMID: 21874228
  5. This publication characterizes the mouse ortholog of the human teashirt zinc finger homeobox 1 gene and proposes that the human gene may be a candidate gene for CAA syndrome. PMID: 17586487

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Involvement in disease
Aural atresia, congenital (CAA)
Subcellular Location
Nucleus.
Protein Families
Teashirt C2H2-type zinc-finger protein family
Tissue Specificity
Expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease.
Database Links

HGNC: 10669

OMIM: 607842

KEGG: hsa:10194

STRING: 9606.ENSP00000323584

UniGene: Hs.284217

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