TXNL1 Antibody

Code CSB-PA025384HA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA025384HA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA025384HA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TXNL1 Polyclonal antibody
Uniprot No.
Target Names
TXNL1
Alternative Names
32 kDa thioredoxin related protein antibody; 32 kDa thioredoxin-related protein antibody; Thioredoxin like 1 antibody; Thioredoxin like 32kD antibody; Thioredoxin like 32kDa antibody; Thioredoxin like protein 1 antibody; Thioredoxin related 32 kDa protein antibody; Thioredoxin-like protein 1 antibody; TRP 32 antibody; TRP32 antibody; TRxL antibody; TXL 1 antibody; TXL antibody; TXL1 antibody; TXN L1 antibody; TXNL 1 antibody; TXNL antibody; Txnl1 antibody; TXNL1_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Thioredoxin-like protein 1 protein (2-289AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TXNL1 Antibody (Product code: CSB-PA025384HA01HU) is Non-conjugated. For TXNL1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA025384HB01HU TXNL1 Antibody, HRP conjugated ELISA
FITC CSB-PA025384HC01HU TXNL1 Antibody, FITC conjugated
Biotin CSB-PA025384HD01HU TXNL1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Active thioredoxin with a redox potential of about -250 mV.
Gene References into Functions
  1. TXNL1 is a novel regulatory molecule that inhibits cisplatin resistance in gastric cancer cells. PMID: 24525731
  2. Distinct protein expression patterns, affecting TXNL1 and HDAC2, distinguish aneuploid with poor prognosis from diploid colorectal cancers. PMID: 21290163
  3. Solution structure of the C-terminal DUF1000 domain of the human thioredoxin-like 1 protein. PMID: 20455272
  4. results imply that TRP-1 is a mammalian thioredoxin and plays as a transcriptional repressor through direct binding to the transcription factor B-Myb PMID: 16231315
  5. TXNL1 acts as an effector of oxidants or a redox sensor by converting redox changes into changes of GDI capacity to capture Rab5, which in turn modulates fluid phase endocytosis PMID: 17987124
  6. Txnl1 is the first example of a direct connection between protein reduction and proteolysis, two major intracellular protein quality control mechanisms. PMID: 19349277
  7. TRP32 was identified as a novel subunit of the 26 S proteasome. PMID: 19349280

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Subcellular Location
Cytoplasm. Nucleus. Note=At least 85% of the cellular TXNL1 is proteasome-associated.
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 12436

OMIM: 603049

KEGG: hsa:9352

STRING: 9606.ENSP00000217515

UniGene: Hs.114412

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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