UBLCP1 Antibody

Code CSB-PA025504GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
UBLCP1
Alternative Names
CPUB1 antibody; CTD like phosphatase domain containing protein antibody; CTD phosphatase like with ubiquitin domain 1 antibody; FLJ25267 antibody; MGC10067 antibody; Nuclear proteasome inhibitor UBLCP1 antibody; UBCP1_HUMAN antibody; Ubiquitin like domain containing CTD phosphatase 1 antibody; Ubiquitin-like domain-containing CTD phosphatase 1 antibody; UBLCP1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human UBLCP1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.
Gene References into Functions
  1. Data show that UBLCP1 selectively binds to the 26S proteasome non-ATPase regulatory subunit 13 (19S regulatory particle) in regulating proteasome assembly. PMID: 28539385
  2. the high-resolution solution structure of the UBL domain of human UBLCP1 and its interaction with Rpn1 PMID: 23667555
  3. UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity PMID: 21949367
Subcellular Location
Nucleus. Note=Colocalizes with nuclear proteasomes.
Tissue Specificity
Broadly expressed, with highest levels in placenta, lung, testis and ovary. Up-regulated in tumor tissues.
Database Links

HGNC: 28110

OMIM: 609867

KEGG: hsa:134510

STRING: 9606.ENSP00000296786

UniGene: Hs.591733

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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