UBP1 Antibody

Code CSB-PA025508GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
UBP1
Alternative Names
UBP1 antibody; LBP1 antibody; Upstream-binding protein 1 antibody; Transcription factor LBP-1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human UBP1
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2. Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box.
Gene References into Functions
  1. Data revealed that dimers composed of LBP-1a and LBP-1c were re-formed probably by a partner-exchange of LBP-1b-containing heterodimers. PMID: 19751393
  2. LBP-1b is an important SF1-independent transcriptional activator stimulating P450scc expression in human placental JEG-3 cells, whereas LBP-9 modulates the action of LBP-1b, exerting both positive and negative effects PMID: 15471945
  3. LBP-1b and LBP-9 both stimulate LBP-32/MGR promoter activity. PMID: 18004979
  4. UBP1 is a critical blood pressure determinant using a combination of mouse and human genetics. PMID: 19662162
Subcellular Location
Nucleus.
Protein Families
Grh/CP2 family, CP2 subfamily
Tissue Specificity
Expressed in adrenal tissue, JEG-3, NCI-H295A, Hep-G2 and HeLa cell lines.
Database Links

HGNC: 12507

OMIM: 609784

KEGG: hsa:7342

STRING: 9606.ENSP00000283628

UniGene: Hs.729120

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