UNC45B Antibody

Code CSB-PA025626GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
UNC45B
Alternative Names
Cardiomyopathy associated 4 antibody; CMYA4 antibody; FLJ38610 antibody; MGC119540 antibody; MGC119541 antibody; OTTHUMP00000163855 antibody; Protein unc 45 homolog B antibody; Protein unc-45 homolog B antibody; SMUNC45 antibody; Striated muscle UNC45 antibody; UN45B_HUMAN antibody; Unc 45 homolog B (C. elegans) antibody; Unc 45 homolog B antibody; UNC 45B antibody; UNC-45B antibody; UNC45 antibody; UNC45B antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human UNC45B
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development.
Gene References into Functions
  1. We have characterized a human UNC45B mutation in a Danish family with autosomal dominant cataract developing in early childhood. PMID: 24549050
  2. temperature-dependent structural changes in the UCS chaperone domain of UNC-45B that occur within a physiologically relevant heat-shock range. PMID: 25436418
Involvement in disease
Cataract 43 (CTRCT43)
Subcellular Location
Cytoplasm, cytosol.
Tissue Specificity
Expressed in eye lens tissues.
Database Links

HGNC: 14304

OMIM: 611220

KEGG: hsa:146862

STRING: 9606.ENSP00000268876

UniGene: Hs.379636

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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