VKORC1L1 Antibody

Datasheet

Code	CSB-PA818673LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA818673LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human stomach tissue using CSB-PA818673LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) VKORC1L1 Polyclonal antibody

Uniprot No.

Q8N0U8

Target Names

VKORC1L1

Alternative Names

VKORC1L1; Vitamin K epoxide reductase complex subunit 1-like protein 1; VKORC1-like protein 1

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Vitamin K epoxide reductase complex subunit 1-like protein 1 protein (38-91AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The VKORC1L1 Antibody (Product code: CSB-PA818673LA01HU) is Non-conjugated. For VKORC1L1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA818673LB01HU	VKORC1L1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA818673LC01HU	VKORC1L1 Antibody, FITC conjugated
Biotin	CSB-PA818673LD01HU	VKORC1L1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Involved in vitamin K metabolism. Can reduce inactive vitamin K 2,3-epoxide to active vitamin K (in vitro), and may contribute to vitamin K-mediated protection against oxidative stress. Plays a role in vitamin K-dependent gamma-carboxylation of Glu residues in target proteins.

Gene References into Functions

This study showed that polymorphisms of EPHX1 and VKORC1L1 could be determinants of stable warfarin doses. PMID: 29054760
a concerted action of the four conserved cysteines of VKORC1L1 for active site regeneration PMID: 24532791
VKORC1L1 is responsible for driving vitamin K-mediated intracellular antioxidation pathways critical to cell survival. PMID: 21367861
VKORC1L1 does not affect the variability of warfarin dose requirement in a Japanese patient population PMID: 17996924

Subcellular Location

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Protein Families

VKOR family

Database Links

HGNC: 21492

OMIM: 608838

KEGG: hsa:154807

STRING: 9606.ENSP00000353998

UniGene: Hs.427232

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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