VOPP1 Antibody

Code CSB-PA03545A0Rb
Size US$166
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  • Western blot
    All lanes: VOPP1 antibody at 2µg/ml
    Lane 1: EC109 whole cell lysate
    Lane 2: 293T whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/15000 dilution
    Predicted band size: 20, 19, 18 kDa
    Observed band size: 50, 70, 80 kDa

  • Immunofluorescent analysis of HepG2 cells using CSB-PA03545A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) VOPP1 Polyclonal antibody
Uniprot No.
Target Names
VOPP1
Alternative Names
VOPP1 antibody; ECOP antibody; GASP antibody; Vesicular antibody; overexpressed in cancer antibody; prosurvival protein 1 antibody; EGFR-coamplified and overexpressed protein antibody; ECop antibody; Glioblastoma-amplified secreted protein antibody; Putative NF-kappa-B-activating protein 055N antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Vesicular, overexpressed in cancer, prosurvival protein 1 protein (23-172AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The VOPP1 Antibody (Product code: CSB-PA03545A0Rb) is Non-conjugated. For VOPP1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA03545B0Rb VOPP1 Antibody, HRP conjugated ELISA
FITC CSB-PA03545C0Rb VOPP1 Antibody, FITC conjugated
Biotin CSB-PA03545D0Rb VOPP1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IF
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.
Gene References into Functions
  1. miR-218 inhibits human lung adenocarcinoma cell migration and invasion via the suppression of Ecop and Robo1 expression PMID: 28936884
  2. Candidate gene eQTL showed a trans-acting association between variants of G protein-coupled receptor kinase 5 gene, previously linked to altered BB response, and high expression of VOPP1. PMID: 26860460
  3. VOPP1 is overexpressed in gastric adenocarcinoma, which is involved in promoting cell proliferation and migration and thus might serve as a putative oncogene. PMID: 25398664
  4. Upregulation of ECOP is associated with glioma. PMID: 23243056
  5. overexpression in cancer participates in the control of the intracellular redox state; its loss leads to oxidative cellular injury leading to cell death by the intrinsic apoptotic pathway PMID: 21519330
  6. ECOP was used as a molecular marker in patients with chronic wounds to guide surgical debridement. PMID: 17515955
  7. Results identify ECOP as a protein relevant to the biology of SCC. PMID: 19525979

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Subcellular Location
Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Note=When overexpressed, localizes in the nucleus and perinuclear regions.
Protein Families
VOPP1/ECOP family
Tissue Specificity
Widely expressed with highest levels in thymus and ovary.
Database Links

HGNC: 34518

OMIM: 611915

KEGG: hsa:81552

STRING: 9606.ENSP00000285279

UniGene: Hs.488307

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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