WDR91 Antibody

Code CSB-PA026077LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA026077LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA026077LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) WDR91 Polyclonal antibody
Uniprot No.
Target Names
WDR91
Alternative Names
HSPC049 antibody; WD repeat containing protein 91 antibody; WD repeat domain 91 antibody; WD repeat-containing protein 91 antibody; WDR 91 antibody; WDR91 antibody; WDR91_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human WD repeat-containing protein 91 protein (1-747AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The WDR91 Antibody (Product code: CSB-PA026077LA01HU) is Non-conjugated. For WDR91 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA026077LB01HU WDR91 Antibody, HRP conjugated ELISA
FITC CSB-PA026077LC01HU WDR91 Antibody, FITC conjugated
Biotin CSB-PA026077LD01HU WDR91 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May play a role in meiosis.
Gene References into Functions
  1. suggest a role for the WDR81-WDR91 complex in the fusion of endolysosomal compartments and the absence of WDR81 leads to impaired receptor trafficking and degradation PMID: 27126989
  2. WDR91 serves as a Rab7 effector that is essential for neuronal development by facilitating endosome conversion in the endosome-lysosome pathway. PMID: 28860274
Subcellular Location
Early endosome membrane; Peripheral membrane protein. Late endosome membrane.
Protein Families
WD repeat WDR91 family
Database Links

HGNC: 24997

KEGG: hsa:29062

STRING: 9606.ENSP00000346466

UniGene: Hs.459858

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