WDR91 Antibody

Datasheet

Code	CSB-PA026077LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA026077LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA026077LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) WDR91 Polyclonal antibody

Uniprot No.

A4D1P6

Target Names

WDR91

Alternative Names

HSPC049 antibody; WD repeat containing protein 91 antibody; WD repeat domain 91 antibody; WD repeat-containing protein 91 antibody; WDR 91 antibody; WDR91 antibody; WDR91_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human WD repeat-containing protein 91 protein (1-747AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The WDR91 Antibody (Product code: CSB-PA026077LA01HU) is Non-conjugated. For WDR91 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA026077LB01HU	WDR91 Antibody, HRP conjugated	ELISA
FITC	CSB-PA026077LC01HU	WDR91 Antibody, FITC conjugated
Biotin	CSB-PA026077LD01HU	WDR91 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May play a role in meiosis.

Gene References into Functions

suggest a role for the WDR81-WDR91 complex in the fusion of endolysosomal compartments and the absence of WDR81 leads to impaired receptor trafficking and degradation PMID: 27126989
WDR91 serves as a Rab7 effector that is essential for neuronal development by facilitating endosome conversion in the endosome-lysosome pathway. PMID: 28860274

Subcellular Location

Early endosome membrane; Peripheral membrane protein. Late endosome membrane.

Protein Families

WD repeat WDR91 family

Database Links

HGNC: 24997

KEGG: hsa:29062

STRING: 9606.ENSP00000346466

UniGene: Hs.459858

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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