YEATS2 Antibody

Code CSB-PA957573
Size US$297
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  • Western blot analysis of extracts from 293 cells, using YEATS2 antiobdy.
  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using YEATS2 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) YEATS2 Polyclonal antibody
Uniprot No.
Target Names
YEATS2
Alternative Names
FLJ10201 antibody; FLJ12841 antibody; FLJ13308 antibody; FLJ33401 antibody; FLJ34335 antibody; KIAA1197 antibody; YEATS domain containing 2 antibody; YEATS domain-containing protein 2 antibody; Yeats2 antibody; YETS2_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human YEATS2.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
IHC 1:50-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr). Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors.
Gene References into Functions
  1. YEATS2 is a selective histone crotonylation reader. PMID: 27103431
  2. YEATS2 gene is highly amplified in human non-small cell lung cancer (NSCLC) and is required for cancer cell growth and survival PMID: 29057918
Subcellular Location
Nucleus.
Database Links

HGNC: 25489

OMIM: 613373

KEGG: hsa:55689

STRING: 9606.ENSP00000306983

UniGene: Hs.632575

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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