ZBTB2 Antibody

Code CSB-PA257697
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA257697(ZBTB2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA257697(ZBTB2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
ZBTB2
Alternative Names
bA351K16.2 antibody; Gm1103 antibody; KIAA1483 antibody; ZBTB2 antibody; ZBTB2_HUMAN antibody; Zinc finger and BTB domain containing 2 antibody; Zinc finger and BTB domain-containing protein 2 antibody; ZNF437 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human ZBTB2
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:10000
IHC 1:30-1:150
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
May be involved in transcriptional regulation.
Gene References into Functions
  1. ZBTB2 may increase cell proliferation by reprogramming glucose metabolic pathways to favor glycolysis by upregulating PDK4 expression via repression of RelA/p65 expression PMID: 25609694
  2. ZBTB2 being considered as a multifunctional cell proliferation activator, notably through p21 repression, this work points out new epigenetic processes potentially involved in carcinogenesis. PMID: 24607898
  3. ZBTB2 is a potential proto-oncogenic master control gene of the p53 pathway and, in particular, is a potent transcription repressor of the cell cycle arrest gene p21 by inhibiting p53 and Sp1 PMID: 19380588
Subcellular Location
Nucleus.
Database Links

HGNC: 20868

OMIM: 616595

KEGG: hsa:57621

STRING: 9606.ENSP00000323183

UniGene: Hs.520073

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