ZNF24 Antibody

Datasheet

Code	CSB-PA171336
Size	US$297
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Image	Western blot analysis of extracts from HUVEC cells, using ZNF24 antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ZNF24 Polyclonal antibody

Uniprot No.

P17028

Target Names

ZNF24

Alternative Names

KOX17 antibody; Retinoic acid suppression protein A antibody; RSG A antibody; RSG-A antibody; RSGA antibody; Zfp191 antibody; Zinc finger and SCAN domain containing protein 3 antibody; Zinc finger and SCAN domain-containing protein 3 antibody; Zinc finger protein 191 antibody; Zinc finger protein 24 antibody; Zinc finger protein KOX17 antibody; ZNF 24 antibody; ZNF191 antibody; ZNF24 antibody; ZNF24_HUMAN antibody; ZSCAN 3 antibody; ZSCAN3 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from N-terminal of Human ZNF24.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence. Has transcription repressor activity in vitro.

Gene References into Functions

miR-940 promoted gastric cancer progression by directly downregulating ZNF24 expression. PMID: 26317898
In vivo, knockdown of ZNF24 specifically in microvascular endothelial cells led to significantly decreased formation of functional vascular networks. PMID: 25550468
results suggest that consecutive ZF1-2 is critical for the regulation of ZNF24 nuclear localization and its transactivation function. PMID: 24224020
ZNF24 may be implicated in transcriptional regulation of genes associated with oncogenesis via interaction with H2A.Z. PMID: 22678762
ZNF191 can directly bind to the CTNNB1 promoter and activate the expression of beta-catenin and its downstream target genes such as cyclin D1 in hepatoma cell lines. PMID: 22213192
These data suggest that ZNF24 is involved in negative regulation of PDGFR-beta and may represent a novel repressor of PDGFR-beta transcription. PMID: 20510677
Overexpression and purification of single zinc finger peptides of ZNF191 were performed. PMID: 17270462
ZNF191 is a pleiotropic factor that has a role in hematopoiesis, brain development, and tumor growth. PMID: 19463170
Data confirm ZNF191 as an essential factor acting for the promotion of the cell cycle and thus maintenance in the progenitor stage. PMID: 19544452

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Subcellular Location

Nucleus.

Protein Families

Krueppel C2H2-type zinc-finger protein family

Tissue Specificity

Expressed in many tissues except in heart.

Database Links

HGNC: 13032

OMIM: 194534

KEGG: hsa:7572

STRING: 9606.ENSP00000261332

UniGene: Hs.514802

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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