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| Code | CSB-AP000851HU |
| Product Type | Chemokine |
| Size |
US$112Purchase it in Cusabio online store (only available for customers from the US) |
| Uniprot No. | P13236 |
| Lead Time | 5-10 business days |
| Image | |
| Storage Buffer | 0.2 μm filtered PBS, pH 7.4 ,lyophilized |
| Alias | G-26 T-lymphocyte-secreted protein, Lymphocyte activation gene 1 protein, LAG-1, MIP-1-beta1-69 |
| Species | Homo sapiens (Human) |
| Biological_Activity | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human CCR5 transfected murine BaF3 cells is less than 2.0 ng/ml, corresponding to a specific activity of >5.0x105 IU/mg. |
| Purity | >97% as determined by SDS-PAGE and HPLC. |
| Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
| Sequence | APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN |
| Research Area | Immunology |
| Source | E.coli |
| Gene Names | CCL4 |
| Expression Region | 24-92aa |
| Tag Info | Tag-Free |
| Mol. Weight | 7.8 kDa |
| Protein Description | Partial of NM_207007.3 |
| PubMed ID | 2462251; 2521882; 2521353; 2247088; 2568930; 1894635; 15843566; 16625196; 15489334; 2809212; 9521068; 8525373; 10540332; 12070155; 12401480; 8134838 |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. |
| Subcellular Location | Secreted |
| Protein Families | Intercrine beta (chemokine CC) family |
| Database Links |
HGNC: 10630 OMIM: 182284 KEGG: hsa:388372 STRING: 9606.ENSP00000250151 UniGene: Hs.449862 |
CCL4 Antibodies for Mus musculus (Mouse)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA09069B0Rb | Ccl4 Antibody, HRP conjugated | Mouse | ELISA |
| CSB-PA09069D0Rb | Ccl4 Antibody, Biotin conjugated | Mouse | ELISA |
| CSB-PA09069A0Rb | Ccl4 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA09069C0Rb | Ccl4 Antibody, FITC conjugated | Mouse | ELISA |
CCL4 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA004797KA01HU | CCL4 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA005136 | CCL4 Antibody | Human | WB,ELISA |
| CSB-PA193639 | CCL4 Antibody | Human,Rat | ELISA,IHC |
CCL4 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA05949A0Rb | CCL4 Antibody | Human | ELISA, IHC |
| CSB-PA05949B0Rb | CCL4 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA05949C0Rb | CCL4 Antibody, FITC conjugated | Human | ELISA |
| CSB-PA05949D0Rb | CCL4 Antibody, Biotin conjugated | Human | ELISA |
CCL4 Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP004797MO CSB-EP004797MO CSB-BP004797MO CSB-MP004797MO |
Recombinant Mouse C-C motif chemokine 4(Ccl4) | Yeast E.coli Baculovirus Mammalian cell |
| CSB-RP090694m | Recombinant Mouse C-C motif chemokine 4(Ccl4) | E.coli |
| CSB-AP001231MO | Recombinant Mouse C-C motif chemokine 4 protein(Ccl4) (Active) | E.coli |
CCL4 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP004797HU CSB-EP004797HU CSB-BP004797HU CSB-MP004797HU |
Recombinant Human C-C motif chemokine 4(CCL4) | Yeast E.coli Baculovirus Mammalian cell |
| CSB-AP000861HU | Recombinant Human C-C motif chemokine 4 protein(CCL4) (Active) | E.coli |
CCL4 Proteins for Oryctolagus cuniculus (Rabbit)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP004797RB CSB-EP004797RB CSB-BP004797RB CSB-MP004797RB |
Recombinant Rabbit C-C motif chemokine 4(CCL4) | Yeast E.coli Baculovirus Mammalian cell |
CCL4 Proteins for Rattus norvegicus (Rat)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP004797RA CSB-EP004797RA CSB-BP004797RA CSB-MP004797RA |
Recombinant Rat C-C motif chemokine 4(Ccl4) | Yeast E.coli Baculovirus Mammalian cell |
| CSB-AP001531RA | Recombinant Rat C-C motif chemokine 4 protein(Ccl4) (Active) | E.coli |
CCL4 Proteins for Bos taurus (Bovine)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP623156BO CSB-EP623156BO CSB-BP623156BO CSB-MP623156BO |
Recombinant Bovine C-C motif chemokine 4(CCL4) | Yeast E.coli Baculovirus Mammalian cell |
CCL4 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP724247DO CSB-EP724247DO CSB-BP724247DO CSB-MP724247DO |
Recombinant Dog C-C motif chemokine 4(CCL4) | Yeast E.coli Baculovirus Mammalian cell |
CCL4 Proteins for Sus scrofa (Pig)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP751243PI CSB-EP751243PI CSB-BP751243PI CSB-MP751243PI |
Recombinant Pig C-C motif chemokine 4(CCL4) | Yeast E.coli Baculovirus Mammalian cell |
CCL4 Proteins for Macaca mulatta (Rhesus macaque)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP810232MOW CSB-EP810232MOW CSB-BP810232MOW CSB-MP810232MOW |
Recombinant Macaca mulatta C-C motif chemokine 4(CCL4) | Yeast E.coli Baculovirus Mammalian cell |
CCL4 Proteins for Gallus gallus (Chicken)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP856190CH CSB-EP856190CH CSB-BP856190CH CSB-MP856190CH |
Recombinant Chicken C-C motif chemokine 4 homolog(CCL4) | Yeast E.coli Baculovirus Mammalian cell |
CCL4 cDNA for Sus scrofa (Pig)
| Code | Product Name | Vector | Accession NO. |
|---|---|---|---|
| CSB-CL751243PI | CCL4 | pUC | NM_213779.1 |
CCL4 cDNA for Macaca mulatta (Rhesus macaque)
| Code | Product Name | Vector | Accession NO. |
|---|---|---|---|
| CSB-CL810232MOW | CCL4L1 | pUC | NM_001032873.1 |
CCL4 cDNA for Gallus gallus (Chicken)
| Code | Product Name | Vector | Accession NO. |
|---|---|---|---|
| CSB-CL856190CH | CCL4 | pUC | NM_001030360.2 |
CCL4 ELISA Kit for Bos taurus (Bovine)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL004797BO | Bovine C-C motif chemokine 4(CCL4) ELISA kit | serum, plasma, tissue homogenates | 5.8 pg/mL |
CCL4 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL004797DO | Dog C-C motif chemokine 4(CCL4) ELISA kit | Request Information |
CCL4 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL004797HU | Human C-C motif chemokine 4(CCL4) ELISA kit | serum, plasma, cell culture supernates, tissue homogenates | 3.9 pg/mL |
CCL4 ELISA Kit for Mus musculus (Mouse)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E04665m | Mouse Macrophage Inflammatory Protein 1β,MIP-1β ELISA kit | serum, plasma, tissue homogenates | 15.6 pg/mL |
CCL4 ELISA Kit for Sus scrofa (Pig)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL004797PI | Pig C-C motif chemokine 4(CCL4) ELISA kit | Request Information |
CCL4 ELISA Kit for Rattus norvegicus (Rat)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E07421r | Rat macrophage inflammatory protein 1β,MIP-1β ELISA kit | serum, plasma, tissue homogenates | 0.78 pg/mL |
Recombinant Rabbit Tissue factor pathway inhibitor(TFPI)
Express system: E.coli
Species: Oryctolagus cuniculus (Rabbit)
Recombinant Human CAMPATH-1 antigen(CD52),partial
Express system: Yeast
Species: Homo sapiens (Human)
Recombinant Human Elongation factor Tu, mitochondrial(TUFM)
Express system: Yeast
Species: Homo sapiens (Human)
Recombinant Human Intestinal-type alkaline phosphatase(ALPI)
Express system: Yeast
Species: Homo sapiens (Human)
Recombinant Human Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial(GATC)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Synaptosomal-associated protein 29(SNAP29)
Express system: E.coli
Species: Homo sapiens (Human)
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