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Code | CSB-AP000851HU |
Size | $2618 |
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Purity | >97% as determined by SDS-PAGE and HPLC. |
Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
Activity | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human CCR5 transfected murine BaF3 cells is less than 2.0 ng/ml, corresponding to a specific activity of >5.0x105 IU/mg. |
Target Names | CCL4L1 |
Uniprot No. | Q8NHW4 |
Research Area | Immunology |
Alternative Names |
CCL4L1; CCL4L; LAG1; SCYA4L1;; CCL4L2; CCL4L; SCYA4L2C-C motif chemokine 4-like; Lymphocyte activation gene 1 protein; LAG-1; Macrophage inflammatory protein 1-beta; MIP-1-beta; Monocyte adherence-induced protein 5-alpha; Small-inducible cytokine A4-like
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Species | Homo sapiens (Human) |
Source | E.Coli |
Expression Region | 24-92aa |
Complete Sequence | APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN |
Mol. Weight | 7.8 kDa |
Protein Length | Full Length of Mature Protein |
Tag Info |
Tag-Free |
Form | Liquid or Lyophilized powder |
Buffer | 0.2 μm filtered PBS, pH 7.4 ,lyophilized |
Troubleshooting and FAQs |
Protein FAQs |
Storage Condition | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Shelf Life | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
Lead Time | 5-10 business days |
Datasheet & COA | Please contact us to get it. |
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Function |
Chemokine that induces chemotaxis of cells expressing CCR5 or CCR1. Inhibits HIV replication in peripheral blood monocytes that express CCR5.
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Subcellular Location | Secreted. |
Protein Families | Intercrine beta (chemokine CC) family |
Tissue Specificity | Detected in B-cells. |
Database Links |
HGNC: 10631 OMIM: 603782 KEGG: hsa:388372 STRING: 9606.ENSP00000405533 UniGene: Hs.449862 |