Recombinant Human C-C motif chemokine 4-like protein(CCL4L1) (Active)

In Stock
Code CSB-AP000851HU
Size $2618
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Product Details

Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human CCR5 transfected murine BaF3 cells is less than 2.0 ng/ml, corresponding to a specific activity of >5.0x105 IU/mg.
Target Names CCL4L1
Uniprot No. Q8NHW4
Research Area Immunology
Alternative Names
CCL4L1; CCL4L; LAG1; SCYA4L1;; CCL4L2; CCL4L; SCYA4L2C-C motif chemokine 4-like; Lymphocyte activation gene 1 protein; LAG-1; Macrophage inflammatory protein 1-beta; MIP-1-beta; Monocyte adherence-induced protein 5-alpha; Small-inducible cytokine A4-like
Species Homo sapiens (Human)
Source E.Coli
Expression Region 24-92aa
Complete Sequence APMGSDPPTA CCFSYTARKL PRNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN
Mol. Weight 7.8 kDa
Protein Length Full Length of Mature Protein
Tag Info Tag-Free
Form Liquid or Lyophilized powder
Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time 5-10 business days
Datasheet & COA Please contact us to get it.

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Target Background

Function
Chemokine that induces chemotaxis of cells expressing CCR5 or CCR1. Inhibits HIV replication in peripheral blood monocytes that express CCR5.
Subcellular Location Secreted.
Protein Families Intercrine beta (chemokine CC) family
Tissue Specificity Detected in B-cells.
Database Links

HGNC: 10631

OMIM: 603782

KEGG: hsa:388372

STRING: 9606.ENSP00000405533

UniGene: Hs.449862

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