Recombinant Human C-C motif chemokine 4-like protein(CCL4) (Active)

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Code CSB-AP000851HU
Product Type Chemokine
Size US$112Purchase it in Cusabio online store
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Uniprot No. Q8NHW4
Lead Time 5-10 business days
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias G-26 T-lymphocyte-secreted protein, Lymphocyte activation gene 1 protein, LAG-1, MIP-1-beta1-69
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human CCR5 transfected murine BaF3 cells is less than 2.0 ng/ml, corresponding to a specific activity of >5.0x105 IU/mg.
Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Research Area Immunology
Source E.coli
Gene Names CCL4
Expression Region 24-92aa
Tag Info Tag-Free
Mol. Weight 7.8 kDa
Protein Description Full Length of Mature Protein
PubMed ID 2462251; 2521882; 2521353; 2247088; 2568930; 1894635; 15843566; 16625196; 15489334; 2809212; 9521068; 8525373; 10540332; 12070155; 12401480; 8134838
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Function Chemokine that induces chemotaxis of cells expressing CCR5 or CCR1. Inhibits HIV replication in peripheral blood monocytes that express CCR5.
Subcellular Location Secreted
Protein Families Intercrine beta (chemokine CC) family
Tissue Specificity Detected in B-cells.
Database Links

HGNC: 10631

OMIM: 603782

KEGG: hsa:388372

STRING: 9606.ENSP00000405533

UniGene: Hs.449862

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