Recombinant Human Protein FAM19A2 protein (FAM19A2) (Active)

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Code CSB-AP001021HU
MSDS
Size $142
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Product Details

Purity
>95% as determined by SDS­PAGE.
Endotoxin
Less than 1.0 EU/μg as determined by LAL method.
Activity
Fully biologically active when compared to standard. The biological activity is determined by its ability to enhance neurite outgrowth of E16?E18 rat embryonic cortical neurons. rHuTAFA?2, immobilized at 6?24 μg/mL on a 96 well plate, is able to significantly enhance neurite outgrowth.
Target Names
FAM19A2
Uniprot No.
Research Area
Immunology
Alternative Names
Chemokine like protein TAFA 2; Chemokine-like protein TAFA-2; Chemokine-like protein TAFA2; DKFZp761E1217; DKFZp781P0552; F19A2_HUMAN; FAM19A2; family with sequence similarity 19 (chemokine (C-C motif)-like); member A2; MGC42403; Protein FAM19A2; TAFA 2; TAFA2
Species
Homo sapiens (Human)
Source
E.coli
Expression Region
31-131aa
Complete Sequence
ANHHKAHHVK TGTCEVVALH RCCNKNKIEE RSQTVKCSCF PGQVAGTTRA APSCVDASIV EQKWWCHMQP CLEGEECKVL PDRKGWSCSS GNKVKTTRVT H
Mol. Weight
11.2 kDa
Protein Length
Full Length of Mature Protein
Tag Info
Tag-Free
Form
Lyophilized powder
Buffer
Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
5-10 business days
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.

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Target Background

Function
Has a role as neurotrophic factor involved in neuronal survival and neurobiological functions.
Gene References into Functions
  1. Data identified two, BCL2 and FAM19A2, novel loci and replicated known variants associated with insulin sensitivity. Further studies are needed to clarify the causal variant and function at the BCL2 and FAM19A2 loci. PMID: 27416945
  2. Variants of FAM19A2 (rs348644) are associated with forced expiratory volume in COPD. PMID: 25112515
  3. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
  4. Observational study of gene-disease association. (HuGE Navigator) PMID: 19240061
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
FAM19/TAFA family
Tissue Specificity
Brain-specific.
Database Links

HGNC: 21589

OMIM: 617496

KEGG: hsa:338811

STRING: 9606.ENSP00000393987

UniGene: Hs.269745

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