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Recombinant Rat C-C motif chemokine protein (Ccl22), partial (Active)

Recombinant Rat C-C motif chemokine protein (Ccl22), partial (Active)

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Code	CSB-AP001581RA
Abbreviation	Recombinant Rat Ccl22 protein, partial (Active)
MSDS	MSDS Datasheet
Size	$142
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Product Details
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Product Details

Purity

>96% as determined by SDS-PAGE.

Endotoxin

Less than 1.0 EU/μg as determined by LAL method.

Activity

Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 10-100 ng/ml.

Target Names

Ccl22

Uniprot No.

Q9QZU1

Research Area

Immunology

Species

Rattus norvegicus (Rat)

Source

E.coli

Expression Region

14-81aa

Complete Sequence

GPYGANVEDS ICCQDYIRHP LPPRFVKEFY WTSKSCRKPG VVLITIKNRD ICADPRMLWV KKILHKLA

Mol. Weight

7.9 kDa

Protein Length

Partial

Tag Info

Tag-Free

Form

Lyophilized powder

Buffer

Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

5-10 business days

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet & COA

Please contact us to get it.

Description

CCL22 (MDC) is a key CCR4 ligand that drives Th2 and regulatory T cell recruitment, making it central to studies of immune tolerance, allergic inflammation, and tumor immune evasion. This tag-free recombinant rat CCL22 (residues 14–81) encompasses the mature protein sequence and demonstrates robust chemotactic activity on human T-lymphocytes at 10–100 ng/ml, supporting direct use in chemotaxis and migration assays, CCR4-dependent signaling pathway analyses, and in vivo rat models of inflammation or tumor biology. Endotoxin levels below 1.0 EU/μg minimize LPS-driven artifacts in sensitive immune cell functional assays, which aligns with standards expected in T cell activation studies, antibody development workflows, and use as a reference standard in cytokine detection platforms such as ELISA. Produced in *E. coli* with purity exceeding 96% by SDS-PAGE, this preparation provides a suitable basis for quantitative bioassays where consistent lot-to-lot potency is essential.