Product Details

Full Product Name

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) ABCB19 Polyclonal antibody

Uniprot No.

Q9LJX0

Target Names

ABCB19

Alternative Names

ABCB19 antibody; MDR1 antibody; MDR11 antibody; PGP19 antibody; At3g28860 antibody; MLD15.2ABC transporter B family member 19 antibody; ABC transporter ABCB.19 antibody; AtABCB19 antibody; Multidrug resistance protein 11 antibody; P-glycoprotein 19 antibody

Raised in

Rabbit

Species Reactivity

Arabidopsis thaliana

Immunogen

Recombinant Arabidopsis thaliana ABCB19 protein

Immunogen Species

Arabidopsis thaliana (Mouse-ear cress)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Target Background

Function

Auxin efflux transporter that acts as a negative regulator of light signaling to promote hypocotyl elongation. Mediates the accumulation of chlorophyll and anthocyanin, as well as the expression of genes in response to light. Participates in auxin efflux and thus regulates the polar auxin basipetal transport (from auxin-producing leaves to auxin-sensitive tissues, and from root tips to root elongating zone). Involved in diverse auxin-mediated responses including gravitropism, phototropism and lateral root formation.

Gene References into Functions

ABCB19 is associated with cytoplasmic streaming and gravitropism in Arabidopsis. PMID: 26337543
Data show ABCB19-mediated polar auxin transport modulates Arabidopsis hypocotyl elongation and the endoreplication variant of the cell cycle. PMID: 26662023
Ion channel activity of ABCB19 that is blocked by NPPB, a compound that can now be considered an inhibitor of polar auxin transport with a defined molecular target. PMID: 25324509
ABCB19 takes part in adventitious root formation in Arabidopsis. PMID: 23677937
The ATP-binding cassette transporter ABCB19 regulates postembryonic organ separation in Arabidopsis. PMID: 23560110
Structural sterols and sphingolipids regulate ABCB19-GFP trafficking between the trans-Golgi network and the plasma membrane. PMID: 23279701
Phosphorylation of ABCB19 by phot1 inhibits its efflux activity, thereby increasing auxin levels in and above the hypocotyl apex. PMID: 21666806
Overexpression of ABCB19 greatly increased auxin in the hypocotyl, which reduced the sensitivity of hypocotyl growth specifically to blue light in long-term assays and red light in high-resolution, short-term assays. PMID: 20088903
The functional characterization of two closely related ABC (ATP-binding cassette) transporter genes, AtMDR1 and AtPGP1, in light and auxin responses. [AtMDR1] PMID: 15908594
Auxin levels established by MDR1-dependent acropetal transport control lateral root growth rate to influence root system architecture. PMID: 17557807
Data show that root hair cell-specific overexpression of auxin efflux transporter PGP19 decreased root hair elongation. PMID: 18156217
This study showed that a defect in the ABC subfamily B auxin transporter ABCB19 suppresses the inhibitory effects of N-1-naphthylphthalamic acid on hypocotyl phototropism and gravitropism, but not on hypocotyl elongation. [AtABCB19] PMID: 18556728
ABCB19 stabilises plasma membrane microdomains that enhance PIN1 auxin transport activity. PMID: 18774968
Cotyledon expansion during the establishment of photoautotrophic growth depends on ABCB19-mediated auxin import. PMID: 19508431

Hide All

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

ABC transporter superfamily, ABCB family, Multidrug resistance exporter (TC 3.A.1.201) subfamily

Tissue Specificity

Ubiquitous, mostly in shoot meristems.

Database Links

KEGG: ath:AT3G28860

STRING: 3702.AT3G28860.1

UniGene: At.24939

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ABCB19 Antibody

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