ABP1 Antibody

Code CSB-PA322813XA01SVG
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ABP1 Polyclonal antibody
Uniprot No.
Target Names
ABP1
Alternative Names
ABP1 antibody; YCR088W antibody; YCR88WActin-binding protein antibody
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) ABP1 protein
Immunogen Species
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Regulates ARP2/3 complex-mediated actin assembly. Recruits ARP2/3 complex to sides of preexisting actin filaments, which may promote nucleation or stabilization of filament branches. Binds to actin filaments, but not actin monomers. Actin binding is required for ARP2/3 complex activation. May also have a role in linking the actin cytoskeleton to endocytosis. recruits components of the endocytotic machinery to cortical actin patches, known sites of endocytosis.
Gene References into Functions
  1. a structural and functional view of the Abp1-actin interaction and demonstration that Abp1 has distinct cellular roles as an adapter, linking different sets of ligands for each function PMID: 15872087
  2. These data provide the first evidence of biological relevance for any Abp1p SH3 domain-mediated interaction. PMID: 17409071
  3. Data imply that the AbpSH3 must bind extended target sites to function efficiently inside the cell. PMID: 19590096
Subcellular Location
Cytoplasm, cytoskeleton, actin patch. Note=Cortical actin patches.
Protein Families
ABP1 family
Database Links

KEGG: sce:YCR088W

STRING: 4932.YCR088W

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