Actn Antibody

Code CSB-PA323567XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Actn Polyclonal antibody
Uniprot No.
Target Names
Actn
Alternative Names
Actn antibody; fliA antibody; l(1)2Cb antibody; CG4376Alpha-actinin antibody; sarcomeric antibody; F-actin cross-linking protein antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Actn protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Gene References into Functions
  1. Flight assays also show that a Zasp52 mutant suppresses the a-actinin mutant phenotype, indicating that both proteins are core structural Z-disc proteins required for optimal Z-disc function. PMID: 27783625
  2. alpha-actinin is involved in the organisation of the cytoskeleton in a non-muscle tissue in Drosophila PMID: 17008069
Subcellular Location
Cytoplasm, myofibril, sarcomere, Z line. Note=Colocalizes with Smn at the Z-line of indirect flight muscles.
Protein Families
Alpha-actinin family
Tissue Specificity
Larval muscle isoform is expressed in the larval body wall, adult muscles of the head and abdomen and supercontractile muscles of the larva and adult. Adult muscle isoform accumulates within adult fibrillar and tubular muscles.
Database Links

KEGG: dme:Dmel_CG4376

STRING: 7227.FBpp0070331

UniGene: Dm.25

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