aex-2 Antibody

Code CSB-PA943936XA01CXY
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Product Details

Full Product Name
Rabbit anti-Caenorhabditis elegans aex-2 Polyclonal antibody
Uniprot No.
Target Names
aex-2
Alternative Names
aex-2 antibody; T14B1.2G-protein coupled receptor aex-2 antibody; Aboc antibody; expulsion defective protein 2 antibody
Raised in
Rabbit
Species Reactivity
Caenorhabditis elegans
Immunogen
Recombinant Caenorhabditis elegans aex-2 protein
Immunogen Species
Caenorhabditis elegans
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
G-protein coupled receptor for the nlp-40 neuropeptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Plays a role in the defecation motor program, which is a coordinated series of three muscle contractions that occurs every 45 seconds. Specifically, acts in GABAergic neurons, such as AVL and DVB, to control the expulsion step of defecation. Required for fatty acid uptake and metabolism by intestinal cells and therefore regulates the levels of triglycerides in the intestine.
Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell projection, cilium.
Protein Families
G-protein coupled receptor 1 family
Tissue Specificity
Expressed in the intestinal muscle, anal depressor, AVL and DVB GABAergic neurons, enteric muscles, the nerve ring, the ventral nerve cord and head mesodermal cells.
Database Links

KEGG: cel:CELE_T14B1.2

STRING: 6239.T14B1.2

UniGene: Cel.19809

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