Code | CSB-PA002208ZA01MO |
Size | US$299 |
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The process of generating the ASGR2 polyclonal antibody adheres to a well-structured procedure. It commences with the repeated immunization of a rabbit using recombinant mouse ASGR2 protein (80-301aa), continuing until the desired antibody titer is reached. Subsequently, the rabbit's blood is collected, and the antibodies are meticulously purified from the serum using protein A/G. The functionality of the resulting ASGR2 antibody is thoroughly assessed through ELISA and WB applications, confirming its specific reactivity with the mouse ASGR2 protein.
The ASGR2 protein is a crucial component of the asialoglycoprotein receptor (ASGPR), facilitating the recognition, uptake, and clearance of desialylated glycoproteins and glycolipids from the bloodstream, particularly in the liver. This function is vital for maintaining metabolic homeostasis and overall health.
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