ATG32 Antibody

Code CSB-PA509790XA01SVL
Size US$299
Image
  • Western Blot
    Positive WB detected in Recombinant protein
    All lanes: ATG32 antibody at 1:2000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 32.8 kDa
    Observed band size: 35 kDa
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Product Details

Full Product Name
Rabbit anti-Saccharomyces cerevisiae (strain JAY291) (Baker's yeast) ATG32 Polyclonal antibody
Uniprot No.
Target Names
ATG32
Alternative Names
ATG32; ECM17; C1Q_04175; Autophagy-related protein 32; Extracellular mutant protein 37
Raised in
Rabbit
Species Reactivity
Saccharomyces cerevisiae (strain JAY291) (Baker's yeast)
Immunogen
Recombinant Saccharomyces cerevisiae (strain JAY291) (Baker's yeast) ATG32 protein
Immunogen Species
Saccharomyces cerevisiae (strain JAY291) (Baker's yeast)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Protein A/G
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

The recombinant Saccharomyces cerevisiae (strain JAY291) (Baker's yeast) ATG32 protein is introduced into a rabbit to trigger an immune reaction. As time passes, the rabbit's immune system produces antibodies against the ATG32 protein. When enough antibodies have been generated, a sample of rabbit serum is gathered to obtain the polyclonal antibodies. The collected serum, which contains the ATG32 antibody, undergoes protein A/G affinity chromatography purification. The effectiveness of the ATG32 antibody is assessed in ELISA and WB applications. This ATG32 antibody can interact with the Saccharomyces cerevisiae (strain JAY291) (Baker's yeast) ATG32 protein.

The Saccharomyces cerevisiae (strain JAY291) ATG32 protein mainly acts as a receptor for mitophagy, which is the selective degradation of mitochondria. ATG32 is involved in the process of autophagy, specifically targeting damaged or unnecessary mitochondria for recycling. It plays a crucial role in maintaining mitochondrial quality control and cellular homeostasis.

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Target Background

Function
Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria. Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Recruits ATG11 to the surface of mitochondria. Promotes also autophagy-dependent peroxisome degradation.
Subcellular Location
Mitochondrion outer membrane; Single-pass membrane protein. Vacuole membrane; Single-pass membrane protein. Preautophagosomal structure membrane; Single-pass membrane protein.
Protein Families
ATG32 family
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