Agr2 Antibody

1. AGR2 accelerates skin wound healing through regulation of cell migration. PMID: 28665039
2. AGR2 induced in ER-stressed and inflammatory pre-neoplastic pancreas is a potential marker of cancer progenitor cells with an important functional role in PDAC initiation. PMID: 27941872
3. impact of AGR2 expression and EGFR signaling on tissue regeneration PMID: 27764193
4. EGFR-mediated signaling in NCI-H460 cells is disrupted with reduced AGR2 expression. PMID: 25666625
5. AGR2 has both intracellular and extracellular effects in the intestine PMID: 25111734
6. Results indicate that DNA methylation within the AGR2 promoter modulates more aggressive cancer cell phenotypes. PMID: 24920423
7. It was concluded that: the expression of AGR2 protein was significantly higher in asthmatic mice as compared with their normal counterparts; the expression was obviously related to the expression of Muc5ac protein and IL-13. PMID: 23392704
8. Agr2 consequently serves to maintain the balance between proliferating and differentiated epithelial cells. PMID: 23209296
9. Agr2 facilitates normal lobuloalveolar development by regulating mammary epithelial cell proliferation; we found no effects on apoptosis in Agr2(-/-) mammary epithelial cells. PMID: 22819674
10. Loss of Foxp1/4 in the developing lung and in postnatal secretory epithelium leads to ectopic activation of the goblet cell fate program, in part, through de-repression of the protein disulfide isomerase anterior gradient 2 (Agr2). PMID: 22675208
11. studies implicate Agr2 in intestinal homeostasis and ER stress and suggest a role in the etiology of inflammatory bowel disease PMID: 20025862
12. AGR2 may be important for the growth and development of the intestine as well as esophageal adenocarcinomas. PMID: 18199544
13. Overexpression of Agr2 is associated with asthma. PMID: 19028979
14. AGR2 is a unique member of the protein disulfide isomerase family, with a specialized and nonredundant role in intestinal mucus production PMID: 19359471

Show More

Hide All

KEGG: mmu:23795

STRING: 10090.ENSMUSP00000020898

UniGene: Mm.7244