Bmp8b Antibody

Code CSB-PA002746ZA01MO
Uniprot No. P55105
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Mouse Bone morphogenetic protein 8B (Bmp8b) (261-399AA)
Raised in Rabbit
Species Reactivity Mus musculus
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Bone morphogenetic protein 8B (BMP-8B), Bmp8b
Immunogen Species Mus musculus (Mouse)
Gene Names Bmp8b
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity). Involved in the generation of primordial germ cells; this function involves Bmp4 in a synergistic manner though separate receptor complexes seem to be involved. Required for the initiation and maintenance of spermatogenesis. Signaling protein involved in regulation of thermogenesis and energy balance. Proposed to increase the peripheral response of brown adipose tissue (BAT) to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT.
Subcellular Location Secreted
Protein Families TGF-beta family
Tissue Specificity Expressed in testis. Expressed in decidual cells of the uterus and in trophoblast cells of the labyrinthine region of the placenta and in the inner root sheath of hair follicles of early postnatal skin. Expressed in the extraembryonic ectoderm in pregastr
Database Links

KEGG: mmu:12164

STRING: 10090.ENSMUSP00000002457

UniGene: Mm.439764

Pathway Hippo signaling pathway
TGF-beta signaling pathway

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