CFTR Antibody

Code CSB-PA282472XA01DIL
Product Type Polyclonal Antibody
Uniprot No. Q1LX78
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) CFTR protein
Raised in Rabbit
Species Reactivity Danio rerio (Zebrafish) (Brachydanio rerio)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Cystic fibrosis transmembrane conductance regulator (EC (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (cAMP-dependent chloride channel) cftr
Immunogen Species Danio rerio (Zebrafish) (Brachydanio rerio)
Gene Names cftr
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis
Subcellular Location Apical cell membrane, Multi-pass membrane protein, Early endosome membrane, Multi-pass membrane protein, Cell membrane, Multi-pass membrane protein, Recycling endosome membrane, Multi-pass membrane protein, Endoplasmic reticulum membrane, Multi-pass membrane protein
Protein Families ABC transporter superfamily, ABCC family, CFTR transporter (TC 3.A.1.202) subfamily
Tissue Specificity Detected in gut epithelium (at protein level) (PubMed:20933420). Detected in kidney, spleen, intestine and liver (PubMed:20732993). Detected in pancreatic duct epithelium at 5 dpf and throughout adult life (PubMed:25592226).
Database Links

KEGG: dre:559080

STRING: 7955.ENSDARP00000060242

UniGene: Dr.74099

Pathway cAMP signaling pathway
AMPK signaling

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