CPL2 Antibody

Code CSB-PA730420XA01DOA
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Product Details

Full Product Name
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) CPL2 Polyclonal antibody
Uniprot No.
Target Names
CPL2
Alternative Names
CPL2 antibody; At5g01270 antibody; F7J8.250RNA polymerase II C-terminal domain phosphatase-like 2 antibody; FCP-like 2 antibody; EC 3.1.3.16 antibody; Carboxyl-terminal phosphatase-like 2 antibody; AtCPL2 antibody; CTD phosphatase-like 2 antibody
Raised in
Rabbit
Species Reactivity
Arabidopsis thaliana
Immunogen
Recombinant Arabidopsis thaliana CPL2 protein
Immunogen Species
Arabidopsis thaliana (Mouse-ear cress)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Processively dephosphorylates 'Ser-5' but not 'Ser-2' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1). This promotes the activity of RNA polymerase II. Together with CPL1, required for male gametes fertility. Multifunctional regulator that modulates plant growth, stress, and phytohormones responses. Positive transcription regulator of genes involved in high salinity resistance and auxin mediated signaling pathway.
Gene References into Functions
  1. Arabidopsis plants that express CPL2 mutants exhibited leaf expansion defects, early flowering, low fertility, and increased salt sensitivity. PMID: 18506580
Subcellular Location
Nucleus. Cytoplasm.
Tissue Specificity
Expressed in seedlings, particularly in tissues undergoing cell division and expansion, petioles, cotyledons vasculature, leaves, shoot and root meristems, and flowers, especially in buds and organs vasculatures.
Database Links

KEGG: ath:AT5G01270

STRING: 3702.AT5G01270.2

UniGene: At.21936

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