CSN1S2 Antibody

Code CSB-PA355862ZA01BO
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Product Details

Full Product Name
Rabbit anti-Bos taurus (Bovine) CSN1S2 Polyclonal antibody
Uniprot No.
Target Names
CSN1S2
Alternative Names
Alpha-S2-casein [Cleaved into: Casocidin-1 (Casocidin-I)], CSN1S2
Raised in
Rabbit
Species Reactivity
Bos taurus
Immunogen
Recombinant Bos taurus CSN1S2 protein
Immunogen Species
Bos taurus (Bovine)
Conjugate
Non-conjugate
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (12-14 weeks)

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Target Background

Function
Important role in the capacity of milk to transport calcium phosphate.; Casocidin-I inhibits the growth of E.coli and S.carnosus.
Gene References into Functions
  1. Translation attenuation via 3' terminal codon usage in bovine mRNA is responsible for the difference in alpha-S2- and beta-casein profile in milk. PMID: 25826667
  2. Data indicate that the pepsin-pancreatin digest of alphaS-Casein exhibited anxiolytic-like activity. PMID: 23580614
  3. Alpha-S2-casein was less effective at preventing fibril formation by modified kappa-casein, whereas alpha- and alpha-S1 casein were comparably potent inhibitors. PMID: 21457703
  4. Single strand conformation polymorphism (SSCP) is a particularly useful technique because it allows discrimination of alleles, including zebu-specific alleles at the CSN2 locus. PMID: 15747725
  5. study reports the SNP and AA change that distinguishes the B allele from other alleles at the CSN1S2 locus PMID: 17582136
  6. Substitution effects of paternal CSN2alpha(s1) allele versus CSN2alpha(s2) allele on protein yield deviations (YDs) are significant, whereas their effects on milk and fat YDs are not. PMID: 18263971
  7. bovine milk alpha s2-casein readily forms fibrils in vitro. Upon incubation at neutral pH & 37 degrees C, spherical particles typical of alpha s2-casein rapidly converted to twisted, ribbon-like fibrils approximately 12 nm in diameter. PMID: 18302322

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Subcellular Location
Secreted.
Protein Families
Alpha-casein family
Tissue Specificity
Mammary gland specific. Secreted in milk.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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