dmd Antibody

Code CSB-PA330993XA01EDZ
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Product Details

Full Product Name
Rabbit anti-Enterobacteria phage T4 (Bacteriophage T4) dmd Polyclonal antibody
Uniprot No.
Target Names
dmd
Alternative Names
dmd antibody; 61.5 antibody; y02BAntitoxin Dmd antibody
Raised in
Rabbit
Species Reactivity
Enterobacteria phage T4 (Bacteriophage T4)
Immunogen
Recombinant Enterobacteria phage T4 (Bacteriophage T4) dmd protein
Immunogen Species
Enterobacteria phage T4 (Bacteriophage T4)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Antitoxin component of a potential type II toxin-antitoxin (TA) system. Acts as an antitoxin against host toxins RnlA and LsoA, preventing them from degrading T4 bacteriophage-derived mRNA and thus permitting successful virus infection. Stabilizes middle (8-10 minutes) and late (18 to 28 minutes) T4 gene transcripts.
Gene References into Functions
  1. This structural study revealed the recognition and inhibition mechanism of RnlA from Escherichia coli by bacteriophage T4 antitoxin Dmd. PMID: 26972252
  2. T4 phage Dmd suppressed the toxicities of both RnlA and LsoA by direct interaction, the first example of a phage with an antitoxin against multiple toxins. PMID: 22403819
Database Links

KEGG: vg:1258668

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