DND1 Antibody

Datasheet
Code CSB-PA809023XA01HU
Product Type Polyclonal Antibody
Uniprot No. Q8IYX4
Delivery Make-to-order
Immunogen Recombinant Homo sapiens (Human) DND1 protein
Raised in Rabbit
Species Reactivity Homo sapiens (Human)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugate
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Dead end protein homolog 1 (RNA-binding motif, single-stranded-interacting protein 4) DND1 RBMS4
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Gene Names DND1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration (By similarity).
Subcellular Location Nucleus, Cytoplasm
Database Links

HGNC: 23799

OMIM: 609385

KEGG: hsa:373863

STRING: 9606.ENSP00000445366

UniGene: Hs.591262

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