DND1 Antibody

Code CSB-PA809023XA01HU
Product Type Polyclonal Antibody
Uniprot No. Q8IYX4
Delivery Make-to-order
Protocols ELISA Protocol
Immunogen Recombinant Homo sapiens (Human) DND1 protein
Raised in Rabbit
Species Reactivity Homo sapiens (Human)
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Dead end protein homolog 1 (RNA-binding motif, single-stranded-interacting protein 4) DND1 RBMS4
Immunogen Species Homo sapiens (Human)
Gene Names DND1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function RNA-binding factor that positively regulates gene expression by prohibiting miRNA-mediated gene suppression. Relieves miRNA repression in germline cells (By similarity). Prohibits the function of several miRNAs by blocking the accessibility of target mRNAs. Sequence-specific RNA-binding factor that binds specifically to U-rich regions (URRs) in the 3' untranslated region (3'-UTR) of several mRNAs. Does not bind to miRNAs. May play a role during primordial germ cell (PGC) survival (By similarity). However, does not seem to be essential for PGC migration (By similarity).
Subcellular Location Nucleus, Cytoplasm
Database Links

HGNC: 23799

OMIM: 609385

KEGG: hsa:373863

STRING: 9606.ENSP00000445366

UniGene: Hs.591262

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